Evaluation of Lyophilization on Efficacy of African Swine Fever Vaccine Candidate ASFV-G-DI177L
This study was to evaluate the ability of the vaccine to be lyophilized, and the stability of the vaccine under different storage conditions.
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This study was to evaluate the ability of the vaccine to be lyophilized, and the stability of the vaccine under different storage conditions.
Overall, this study provides data on novel diagnostic sample types in a unique natural consumption model with potential benefits towards enhanced surveillance and early ASFV detection.
Partnering to expand testing capacities, support further evaluation and validation of two commercially available CSF PCR assays, and enhance preparedness across the NAHLN.
In this study, we aim to explore the potential of mRNA vaccine technology for the development of a subunit vaccine against ASFV. For this pilot project, we focused on assessing the immunogenicity of mRNA vaccines containing four well-characterized ASFV antigens: p32, p54, C-type lectin, and CD2v. Each of these antigens plays a distinct role in the viral lifecycle.
The objective of this study was to estimate and compare the diagnostic performance of a novel indirect enzyme-linked immunosorbent assay (iELISA) for ASF serum antibodies (iELISA), developed by Innoceleris Ames, IA, USA and produced and commercialized by Tetracore (Rockville, MD, USA), and the VetAlert™ ASFV DNA Test Kit (qPCR, Tetracore) in both serum and oral fluid (OF) samples collected on farms in Vietnam.